WFYI Indianapolis

How do Darwinian principles explain the resilience of cancer cells?

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Air date: October 28, 2012

Host: Barbara Lewis

Cancer Research
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Interview: Kathy Miller, M.D.



Researchers at the Moffitt Cancer Center in Tampa, Fla., recently published a paper that concluded that cancer cells become resistant to targeted chemotherapies because they can quickly evolve to fit their environments through the Darwinian principle of natural selection. Kathy Miller, M.D., a professor at the IU Simon Cancer Center, talks with Host Barbara Lewis about how this idea dictates everyday practice and treatment, including finding effective treatments for specialized cancer cells with a selective advantage. Miller speculates on the possibility of cancer specialists anticipating the evolution of cancer cells to make treatments more effective in the future.